Filgotinib

Chemical formula: C₂₁H₂₃N₅O₃S  Molecular mass: 425.51 g/mol 

Therapeutic indications

Filgotinib is indicated for:

Rheumatoid arthritis

Population group: only adults (18 - 65 years old)

Filgotinib is indicated for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs). Filgotinib may be used as monotherapy or in combination with methotrexate (MTX).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Rheumatoid arthritis

Population group: only elderly (65 years old or older)

Filgotinib is indicated for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs). Filgotinib may be used as monotherapy or in combination with methotrexate (MTX).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ulcerative colitis

Population group: only adults (18 years old or older)

Filgotinib is indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic agent.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Filgotinib is contraindicated in the following cases:

Active tuberculosis

Tuberculosis

Active serious infections

Infectious disease

Pregnancy

Pregnancy

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