Chemical formula: C₁₂H₁₁ClN₂O₅S Molecular mass: 330.744 g/mol PubChem compound: 3440
Furosemide inhibits active chloride transport in the thick ascending limb. Re-absorption of sodium, chloride from the nephron is reduced and a hypotonic or isotonic urine produced. The evidence from many experimental studies suggests that furosemide acts along the entire nephron with the exception of the distal exchange site.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03CA01 | Furosemide | C Cardiovascular system → C03 Diuretics → C03C High-ceiling diuretics → C03CA Sulfonamides, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FUROSEMIDE TABLETS BP Uncoated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FUROSEMIDE Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Furosemide is an active ingredient of these brands:
United States (US)Albania (AL)Austria (AT)
Brazil (BR)
Canada (CA)Estonia (EE)
Finland (FI)
Germany (DE)
Israel (IL)Italy (IT)Japan (JP)Lithuania (LT)Mexico (MX)
Netherlands (NL)Nigeria (NG)Romania (RO)
South Africa (ZA)Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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