Gabapentin

Chemical formula: C₉H₁₇NO₂  Molecular mass: 171.237 g/mol  PubChem compound: 3446

Active ingredient description

Gabapentin readily enters the brain and prevents seizures in a number of animal models of epilepsy. Gabapentin binds with high affinity to the α2δ (alpha-2-delta) subunit of voltage-gated calcium channels and it is proposed that binding to the α2δ subunit may be involved in gabapentin’s anti-seizure effects in animals.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02BF01 Gabapentin N Nervous system → N02 Analgesics → N02B Other analgesics and antipyretics → N02BF Gabapentinoids
Discover more medicines within N02BF01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NEURONTIN Capsule / Film-coated tablet / Solution FDA, National Drug Code (US) MPI, US: SPL/PLR
NEURONTIN Capsule, hard Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 60142-96-3
DrugBank Drug: DB00996
KEGG Drug: D00332
PubChem Compound: 3446
RxNorm Ingredient: 25480
SNOMED-CT Concept: 386845007
Gabapentin (substance)
UNII Identifier: 6CW7F3G59X
GABAPENTIN

Medicines

Gabapentin is an active ingredient of these brands:

United States (US)

Albania (AL)

Austria (AT)

Canada (CA)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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