Molecular mass: 432.557 g/mol
Hydrocortisone butyrate is the butyrate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D07AB02 | Hydrocortisone butyrate | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AB Corticosteroids, moderately potent (group II) |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LOCOID Cream | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| LOCOID Lotion, 0.1% | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Hydrocortisone butyrate is an active ingredient of these brands:
United States (US)Finland (FI)France (FR)Ireland (IE)Japan (JP)Lithuania (LT)Mexico (MX)Netherlands (NL)New Zealand (NZ)Romania (RO)South Africa (ZA)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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