Isosorbide dinitrate Other names: Dilatrate

Chemical formula: C₆H₈N₂O₈  Molecular mass: 236.136 g/mol  PubChem compound: 6883

Active ingredient description

Isosorbide dinitrate is an organic nitrate, which in common with other cardioactive nitrates, is a vasodilator.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01DA08 Isosorbide dinitrate C Cardiovascular system → C01 Cardiac therapy → C01D Vasodilators used in cardiac diseases → C01DA Organic nitrates
Discover more medicines within C01DA08
C05AE02 Isosorbide dinitrate C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AE Muscle relaxants
Discover more medicines within C05AE02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ISOKET 1 mg/ml Concentrate for solution for injection / infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ISOSORBIDE DINITRATE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ISORDIL TITRADOSE Tablet FDA, National Drug Code (US) MPI, US: SPL/Old
ISOKET RETARD Prolonged release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 87-33-2
DrugBank Drug: DB00883
KEGG Drug: D00516
PubChem Compound: 6883
RxNorm Ingredient: 6058
SNOMED-CT Concept: 387332007
Isosorbide dinitrate (substance)
UNII Identifier: IA7306519N
ISOSORBIDE DINITRATE

Medicines

Isosorbide dinitrate is an active ingredient of these brands:

United States (US)

Albania (AL)

Australia (AU)

Brazil (BR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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