Ivabradine

Chemical formula: C₂₇H₃₆N₂O₅  Molecular mass: 468.594 g/mol  PubChem compound: 132999

Active ingredient description

Ivabradine is a pure heart rate lowering agent, acting by selective and specific inhibition of the cardiac pacemaker If current that controls the spontaneous diastolic depolarisation in the sinus node and regulates heart rate. The cardiac effects are specific to the sinus node with no effect on intra-atrial, atrioventricular or intraventricular conduction times, nor on myocardial contractility or ventricular repolarisation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01EB17 Ivabradine C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EB Other cardiac preparations
Discover more medicines within C01EB17

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PROCORALAN Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 155974-00-8
DrugBank Drug: DB09083
KEGG Drug: D07165
PubChem Compound: 132999
RxNorm Ingredient: 1649480
SNOMED-CT Concept: 421228002
Ivabradine (substance)
UNII Identifier: 3H48L0LPZQ
IVABRADINE

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