Ivermectin

Active ingredient description

Ivermectin is a member of the avermectin class and has high affinity with glutamate-gated chloride channels present in invertebrate nerve and muscle cells. Its binding to these channels promotes an increase in membrane permeability to chloride ions, leading to hyperpolarization of the neural or muscle cell. This results in neuromuscular paralysis and may lead to the death of certain parasites.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Ivermectin
D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AX Other dermatologicals
Discover more medicines within D11AX22
Ivermectin
P Antiparasitic products, insecticides and repellents → P02 Anthelmintics → P02C Antinematodal agents → P02CF Avermectines
Discover more medicines within P02CF01

Medicines

Ivermectin is the active ingredient of these drugs:

Drug
Countries

Spain

Brazil

Brazil

Brazil

Poland

Brazil

Canada

Austria

Finland

United States

Austria Brazil Cyprus Finland France

Australia Canada France Netherlands New Zealand

Brazil

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
NL

Unique ingredient identifier (UNII)

8883YP2R6D - IVERMECTIN

CAS registry number

70288-86-7 - ivermectin

SNOMED-CT

387559003 - Ivermectin (substance)