Ivermectin is a member of the avermectin class and has high affinity with glutamate-gated chloride channels present in invertebrate nerve and muscle cells. Its binding to these channels promotes an increase in membrane permeability to chloride ions, leading to hyperpolarization of the neural or muscle cell. This results in neuromuscular paralysis and may lead to the death of certain parasites.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Ivermectin is the active ingredient of these drugs:
Spain
Brazil
Brazil
Brazil
Poland
Brazil
Canada
Austria
Finland
United States
Austria Brazil Cyprus Finland France
Australia Canada France Netherlands New Zealand
Brazil
Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):