Ketorolac Other names: Ketorolac trometamol

Chemical formula: C₁₅H₁₃NO₃  Molecular mass: 255.269 g/mol  PubChem compound: 3826

Active ingredient description

Ketorolac is a non-steroidal anti-inflammatory agent demonstrating analgesic and anti-inflammatory activity. Ketorolac inhibits the cyclo-oxygenase enzyme essential for biosynthesis of prostaglandins. Ketorolac has been shown to reduce prostaglandin levels in the aqueous humour after topical ophthalmic administration.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
M01AB15 Ketorolac M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AB Acetic acid derivatives and related substances
Discover more medicines within M01AB15
S01BC05 Ketorolac S Sensory organs → S01 Ophthalmologicals → S01B Antiinflammatory agents → S01BC Antiinflammatory agents, non-steroids
Discover more medicines within S01BC05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ACUVAIL Ophthalmic solution FDA, National Drug Code (US) MPI, US: SPL/PLR
ACULAR Eye drops, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 74103-06-3
DrugBank Drug: DB00465
KEGG Drug: D08104
PubChem Compound: 3826
RxNorm Ingredient: 35827
SNOMED-CT Concept: 372501008
Ketorolac (substance)
UNII Identifier: YZI5105V0L
KETOROLAC

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