Lenalidomide

Chemical formula: C₁₃H₁₃N₃O₃  Molecular mass: 259.261 g/mol  PubChem compound: 216326

Therapeutic indications

Lenalidomide is indicated for:

Multiple myeloma

Population group: only adults (18 - 65 years old)

Lenalidomide as monotherapy is indicated for the maintenance treatment of adult patients with newly diagnosed multiple myeloma who have undergone autologous stem cell transplantation.

Lenalidomide as combination therapy with dexamethasone, or bortezomib and dexamethasone, or melphalan and prednisone is indicated for the treatment of adult patients with previously untreated multiple myeloma who are not eligible for transplant.

Lenalidomide in combination with dexamethasone is indicated for the treatment of multiple myeloma in adult patients who have received at least one prior therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Myelodysplastic syndromes

Population group: only adults (18 - 65 years old)

Revlimid as monotherapy is indicated for the treatment of adult patients with transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Mantle cell lymphoma

Population group: only adults (18 - 65 years old)

Lenalidomide as monotherapy is indicated for the treatment of adult patients with relapsed or refractory mantle cell lymphoma.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Lenalidomide is contraindicated in the following cases:

Pregnancy

Pregnancy

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