Levocetirizine

Chemical formula: C₂₁H₂₅ClN₂O₃  Molecular mass: 388.89 g/mol  PubChem compound: 1549000

Active ingredient description

Levocetirizine, the ® enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors. Pharmacodynamic studies in healthy volunteers demonstrate that, at half the dose, levocetirizine has comparable activity to cetirizine, both in the skin and in the nose.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R06AE09 Levocetirizine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AE Piperazine derivatives
Discover more medicines within R06AE09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
XYZAL Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 130018-77-8
DrugBank Drug: DB06282
KEGG Drug: D07402
PubChem Compound: 1549000
RxNorm Ingredient: 356887
SNOMED-CT Concept: 421889003
Levocetirizine (substance)
UNII Identifier: 6U5EA9RT2O
LEVOCETIRIZINE

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