Levosimendan

Chemical formula: C₁₄H₁₂N₆O  Molecular mass: 280.285 g/mol  PubChem compound: 3033825

Interactions

Levosimendan interacts in the following cases:

Mild to moderate renal impairment, mild to moderate hepatic impairment

Levosimendan should be used cautiously in patients with mild to moderate renal or mild to moderate hepatic impairment. Only limited data are available in patients with impaired renal function. Impaired hepatic or renal function may lead to increased concentrations of the metabolite, which may result in more pronounced and prolonged haemodynamic effects.

Pregnancy

There is no experience of using levosimendan in pregnant women. Animal studies have shown toxic effects on reproduction. Therefore, levosimendan should be used in pregnant women only if the benefits for the mother outweigh the possible risks to the foetus.

Nursing mothers

It is not known whether levosimendan is excreted in human milk, therefore, women receiving levosimendan should not breastfeed.

Carcinogenesis, mutagenesis and fertility

Fertility

No data available.

Effects on ability to drive and use machines

No data available.

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Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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