Melatonin Other names: N-acetyl-5-methoxytryptamine Pineal Hormone

Chemical formula: C₁₃H₁₆N₂O₂  Molecular mass: 232.278 g/mol  PubChem compound: 896

Active ingredient description

Melatonin is a naturally occurring hormone produced by the pineal gland and is structurally related to serotonin. Physiologically, melatonin secretion increases soon after the onset of darkness, peaks at 2-4 am and diminishes during the second half of the night. Melatonin is associated with the control of circadian rhythms and entrainment to the light-dark cycle. It is also associated with a hypnotic effect and increased propensity for sleep.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05CH01 Melatonin N Nervous system → N05 Psycholeptics → N05C Hypnotics and sedatives → N05CH Melatonin receptor agonists
Discover more medicines within N05CH01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CIRCADIN Prolonged-release tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 73-31-4
DrugBank Drug: DB01065
KEGG Drug: D08170
PubChem Compound: 896
RxNorm Ingredient: 6711
SNOMED-CT Concept: 41199001
Melatonin (substance)
UNII Identifier: JL5DK93RCL
MELATONIN

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