Methylthioninium chloride Other names: Methylene blue

Chemical formula: C₁₆H₁₈ClN₃S  Molecular mass: 319.85 g/mol  PubChem compound: 6099

Active ingredient description

In vivo, in low concentration, methylthioninium chloride speeds up the conversion of methaemoglobin to haemoglobin. Methylthioninium chloride has been observed to stain tissues selectively.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V03AB17 Methylthioninium chloride V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AB Antidotes
Discover more medicines within V03AB17
V04CG05 Methylthioninium chloride V Various → V04 Diagnostic agents → V04C Other diagnostic agents → V04CG Tests for gastric secretion
Discover more medicines within V04CG05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
METHYLTHIONINIUM CHLORIDE PROVEBLUE Solution for injection European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 61-73-4
DrugBank Drug: DB09241
PubChem Compound: 6099
SNOMED-CT Concept: 6725000
Methylthioninium chloride (substance)
UNII Identifier: T42P99266K
METHYLENE BLUE

Medicines

Methylthioninium chloride is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

  • (combination) CYSTEX as METHYLENE BLUE ANHYDROUS
  • (combination) SEPURIN as METHYLENE BLUE ANHYDROUS

Croatia (HR)

Estonia (EE)

France (FR)

Ireland (IE)

Italy (IT)

Lithuania (LT)

New Zealand (NZ)

Poland (PL)

Turkey (TR)

  • BLUMET as METHYLENE BLUE ANHYDROUS

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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