Metoprolol
Chemical formula: C₁₅H₂₅NO₃ Molecular mass: 267.364 g/mol PubChem compound: 4171
Active ingredient description
Metoprolol is a cardioselective beta-adrenergic blocking agent. It has a relatively greater blocking effect on beta1-receptors (ie those mediating adrenergic stimulation of heart rate and contractility and release of free fatty acids from fat stores) than on beta2-receptors, which are chiefly involved in broncho and vasodilation.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| C07AB02 | Metoprolol | C Cardiovascular system → C07 Beta blocking agents → C07A Beta blocking agents → C07AB Beta blocking agents, selective |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| BETALOC Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| TOPROL XL Extended-release tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| METOPROLOL TARTRATE Tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Metoprolol is an active ingredient of these brands:
Albania (AL)
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)Israel (IL)Italy (IT)Japan (JP)Lithuania (LT)
Malta (MT)Mexico (MX)
Netherlands (NL)New Zealand (NZ)Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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