Nirmatrelvir Other names: PF-07321332

Chemical formula: C₂₃H₃₂F₃N₅O₄  Molecular mass: 499.535 g/mol 

Active ingredient description

Nirmatrelvir (drug development code: PF-07321332), is a potent and selective peptidomimetic inhibitor of the SARS-CoV-2 3-chymotrypsin like protease, a virally encoded enzyme that is critical to the SARS-CoV-2 replication cycle.

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PAXLOVID Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 2628280-40-8
DrugBank Drug: DB16691
KEGG Drug: D12244
RxNorm Ingredient: 2587892
UNII Identifier: 7R9A5P7H32
NIRMATRELVIR

Medicines

Nirmatrelvir is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Canada (CA)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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