Nitrofurantoin

Chemical formula: C₈H₆N₄O₅  Molecular mass: 238.159 g/mol  PubChem compound: 6604200

Active ingredient description

Nitrofurantoin is a broad spectrum antibacterial agent, active against the majority of urinary pathogens. It is bactericidal in renal tissue and throughout the urinary tract. The wide range of organisms sensitive to the bacterial activity include Escherichia coli, Enteroccus faecalis, Klebsiella species, Enterobacter species, Staphylococcus species: (e.g. S. aureus, S. saprophyticus, S. epidermidis).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01XE01 Nitrofurantoin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XE Nitrofuran derivatives
Discover more medicines within J01XE01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NITROFURANTOIN Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MACROBID Prolonged-release capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 67-20-9
DrugBank Drug: DB00698
KEGG Drug: D00439
PubChem Compound: 6604200
RxNorm Ingredient: 7454
SNOMED-CT Concept: 373543005
Nitrofurantoin (substance)
UNII Identifier: 927AH8112L
NITROFURANTOIN

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