Nitrofurantoin

Chemical formula: C₈H₆N₄O₅  Molecular mass: 238.159 g/mol  PubChem compound: 6604200

Therapeutic indications

Nitrofurantoin is indicated for:

Lower urinary tract infections, pyelitis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For the treatment against acute or recurrent, uncomplicated lower urinary tract infections or pyelitis, either spontaneous or following surgical procedures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of lower urinary tract infections, pyelitis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For the prophylaxis against acute or recurrent, uncomplicated lower urinary tract infections or pyelitis, either spontaneous or following surgical procedures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Lower urinary tract infections, pyelitis

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old)

For the treatment against acute or recurrent, uncomplicated lower urinary tract infections or pyelitis, either spontaneous or following surgical procedures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Nitrofurantoin is contraindicated in the following cases:

Pregnancy

Pregnancy

Acute porphyria

Acute intermittent porphyria

G6PD deficiency

Deficiency of glucose-6-phosphate dehydrogenase

Renal dysfunction (eGFR of less than 45 ml/minute)

at least one of


Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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