Pimavanserin

Chemical formula: C₂₅H₃₄FN₃O₂  Molecular mass: 427.564 g/mol  PubChem compound: 10071196

Active ingredient description

Pimavanserin is an atypical antipsychotic indicated for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. The mechanism of action of is unclear. However, the effect of pimavanserin could be mediated through a combination of inverse agonist and antagonist activity at serotonin 5-HT2A receptors and to a lesser extent at serotonin 5-HT2C receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05AX17 N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AX Other antipsychotics
Discover more medicines within N05AX17

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NUPLAZID Capsule FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 706779-91-1
DrugBank Drug: DB05316
PubChem Compound: 10071196
RxNorm Ingredient: 1791685
SNOMED-CT Concept: 721997002
Pimavanserin (substance)
UNII Identifier: JZ963P0DIK
PIMAVANSERIN

Medicines

Pimavanserin is an active ingredient of these brands:

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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