Progesterone Other names: P4

Chemical formula: C₂₁H₃₀O₂  Molecular mass: 314.462 g/mol  PubChem compound: 5994

Therapeutic indications

Progesterone is indicated for:

Hormone replacement therapy (HRT)

Population group: women, only adults (18 - 65 years old)

Progesterone is indicated for adjunctive use with estrogen in post-menopausal women with an intact uterus, as hormone replacement therapy (HRT).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Infertility due to inadequate luteal phase

Population group: women, only adults (18 - 65 years old)

Treatment of infertility due to inadequate luteal phase.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Infertility due to tubal, idiopathic or endometriosis linked sterility

Population group: only adults (18 - 65 years old)

For use during in-vitro fertilisation, where infertility is mainly due to tubal, idiopathic or endometriosis linked sterility associated with normal ovulatory cycles.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Progesterone is contraindicated in the following cases:

Hypersensitivity to progesterone

Progesterone allergy

Lactation

Lactation

Cerebral haemorrhage

Cerebral hemorrhage

Porphyria

Porphyria

Liver disease

Hepatopathy

Thrombophilic disorders

Thrombophilia

Thromboembolism disorders, thrombophlebitis

at least one of
Thromboembolism of vein
Venous thrombosis
Venous embolism
Pulmonary embolism
Thrombophlebitis

Genital bleeding

Hemorrhage of genital region

Estrogen-dependent malignant tumours

Estrogen receptor positive tumor

Breast cancer

Malignant tumor of breast

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