Quinidine

Chemical formula: C₂₀H₂₄N₂O₂  Molecular mass: 324.417 g/mol  PubChem compound: 441074

Active ingredient description

Quinidine increases plasma levels of dextromethorphan by competitively inhibiting cytochrome P450 2D6 (CYP2D6), which catalyses a major biotransformation pathway for dextromethorphan.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01BA01 Quinidine C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BA Antiarrhythmics, class Ia
Discover more medicines within C01BA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
QUINIDINE SULFATE Tablet FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1476-98-8
DrugBank Drug: DB00908
KEGG Drug: D08458
PubChem Compound: 441074
RxNorm Ingredient: 9068
SNOMED-CT Concept: 372697008
Quinidine (substance)
UNII Identifier: ITX08688JL
QUINIDINE

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