Ramipril

Active ingredient description

Ramiprilat, the active metabolite of the prodrug ramipril, inhibits the enzyme dipeptidylcarboxypeptidase I (synonyms: angiotensin-converting enzyme; kininase II). In plasma and tissue this enzyme catalyses the conversion of angiotensin I to the active vasoconstrictor substance angiotensin II, as well as the breakdown of the active vasodilator bradykinin. Reduced angiotensin II formation and inhibition of bradykinin breakdown lead to vasodilatation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Ramipril
C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain
Discover more medicines within C09AA05

Medicines

Ramipril is the active ingredient of these drugs:

Drug
Countries

Cyprus

Spain

Canada United States

Lithuania Poland

Poland

Poland

Poland

Finland Lithuania

Germany

Poland

Brazil

Italy

Lithuania

Italy

Austria

Poland

Italy

Austria

Brazil

Italy

Poland

Poland

Lithuania

Poland

Tunisia

Australia

Italy

Australia

Ireland

Germany

Lithuania Poland

Lithuania

Hong Kong

Germany

Ireland

Cyprus Lithuania

Poland

Ireland

Tunisia

Poland

Tunisia

Italy

Brazil Cyprus France Italy Tunisia

Australia Austria Hong Kong Ireland Poland

Australia New Zealand

Italy

Ramipril is also found within below combination drugs:

ALAMUT , ALTACE HCT , AMPRIL HD , AMPRIL HL , AMRAP , ARELIX ACE , CARDACE COMP , CORAPRIL , COREYRA , COTRIATEC , DELIX PLUS , DELMUNO , DUOTENS , EGIRAMLON , HARTIL HCT , HERZAPLUS , HYPREN-PLUS , ICOMB , IDROQUARK , KASTEL , KRUPLUS , LANNAPRIL-PLUS , LASITACE , NAPRIX A , NAPRIX D , NORAZIDE , PARVATI , PREMINOR , PRESUCOMB , PRYLAR , RAMANTAL , RAMDACORDIA , RAMI-AMLO , RAMICOMP , RAMICOR COMB , RAMIDIPIN , RAMILICH COMP , RAMIMED HCT , RAMIPLUS , RAMIZEK COMBI , RAMIZEK HCT , RAMLADIO , RAMLON , RAMOSTIN , RIMAL , SAMBETAN , SUMILAR , SUMILAR HCT , TONOTEC , TRIACOR , TRIAMLO , TRIAPIN , TRIASYN , TRIATEC HCT , TRIATEC PLUS , TRINOMIA , TRITACE COMB , TRITAMLO , TRITAZIDE , UNIPRILDIUR

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Structured Product Labeling (SPL/PLR)
US
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

L35JN3I7SJ - RAMIPRIL

CAS registry number

87333-19-5 - ramipril

SNOMED-CT

386872004 - Ramipril (substance)