Repaglinide

Chemical formula: C₂₇H₃₆N₂O₄  Molecular mass: 452.586 g/mol  PubChem compound: 65981

Therapeutic indications

Repaglinide is indicated for:

Diabetes mellitus type 2

Population group: only adults (18 - 65 years old)

Repaglinide is indicated in adults with type 2 diabetes mellitus whose hyperglycaemia can no longer be controlled satisfactorily by diet, weight reduction and exercise. Repaglinide is also indicated in combination with metformin in adults with type 2 diabetes mellitus who are not satisfactorily controlled on metformin alone.

Treatment should be initiated as an adjunct to diet and exercise to lower the blood glucose in relation to meals.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Repaglinide is contraindicated in the following cases:

Diabetes mellitus type 1, C-peptide negative

Diabetes mellitus type I

Diabetic ketoacidosis

Diabetic ketoacidosis

Severe hepatic function disorder

Hepatic failure stage IV

Gemfibrozil

Gemfibrozil

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