Rimonabant

Chemical formula: C₂₂H₂₁Cl₃N₄O  Molecular mass: 463.787 g/mol  PubChem compound: 104850

Active ingredient description

Rimonabant is a selective cannabinoid-1 receptor (CB1) antagonist that inhibits the pharmacological effects of cannabinoid agonists in vitro and in vivo. The endocannabinoid system is a physiological system present in brain and peripheral tissues (including adipocytes) that affects energy balance, glucose and lipid metabolism and body weight, and in neurons of the mesolimbic system modulates the intake of highly palatable, sweet or fatty foods.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A08AX01 Rimonabant A Alimentary tract and metabolism → A08 Antiobesity preparations, excl. diet products → A08A Antiobesity preparations, excl. diet products → A08AX Other antiobesity drugs
Discover more medicines within A08AX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ACOMPLIA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 168273-06-1
DrugBank Drug: DB06155
KEGG Drug: D05731
PubChem Compound: 104850
SNOMED-CT Concept: 422794008
Rimonabant (substance)
UNII Identifier: RML78EN3XE
RIMONABANT

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