Rolapitant

Chemical formula: C₂₅H₂₆F₆N₂O₂  Molecular mass: 500.485 g/mol  PubChem compound: 10311306

Active ingredient description

Rolapitant is a selective antagonist of human substance P/neurokinin 1 (NK1) receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A04AD14 A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AD Other antiemetics
Discover more medicines within A04AD14

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VARUBY Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 552292-08-7
DrugBank Drug: DB09291
KEGG Drug: D10742
PubChem Compound: 10311306
RxNorm Ingredient: 1665496
SNOMED-CT Concept: 715254008
Rolapitant (substance)
UNII Identifier: NLE429IZUC
ROLAPITANT

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