Selinexor

Chemical formula: C₁₇H₁₁F₆N₇O  Molecular mass: 443.313 g/mol  PubChem compound: 71481097

Therapeutic indications

Selinexor is indicated for:

Multiple myeloma - combination treatment with bortezomib and dexamethasone

Population group: only adults (18 years old or older)

Selinexor is indicated in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Multiple myeloma - combination treatment with dexamethasone

Population group: only adults (18 years old or older)

Selinexor is indicated in combination with dexamethasone for the treatment of multiple myeloma in adult patients who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, two immunomodulatory agents and an anti-CD38 monoclonal antibody, and who have demonstrated disease progression on the last therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Selinexor is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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