Semaglutide

Chemical formula: C₁₈₇H₂₉₁N₄₅O₅₉  Molecular mass: 4,113.641 g/mol 

Therapeutic indications

Semaglutide is indicated for:

Diabetes mellitus type 2

Population group: only adults (18 - 65 years old)

Semaglutide is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:

  • as monotherapy when metformin is considered inappropriate due to intolerance or contraindications.
  • in addition to other medicinal products for the treatment of diabetes.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Semaglutide is contraindicated in the following cases:

Congestive heart failure NYHA class IV

Heart failure New York Heart Assosiation Class IV

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Pregnancy

Pregnancy

Breast-feeding

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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