The sugar moiety of the sennosides is removed by bacteria in the large intestine releasing the active anthrone fraction. This stimulates peristalsis via the submucosal and myenteric nerve plexuses.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A06AB06 | Senna glycosides | A Alimentary tract and metabolism → A06 Laxatives → A06A Laxatives → A06AB Contact laxatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SENOKOT Syrup | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Sennosides is an active ingredient of these brands:
Australia (AU)
Canada (CA)
Ecuador (EC)Estonia (EE)
France (FR)
Hong Kong (HK)Lithuania (LT)Malta (MT)
Netherlands (NL)New Zealand (NZ)
Singapore (SG)South Africa (ZA)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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