Solifenacin

Chemical formula: C₂₃H₂₆N₂O₂  Molecular mass: 362.473 g/mol  PubChem compound: 154059

Active ingredient description

Solifenacin is a competitive, specific cholinergic-receptor antagonist. In vitro and in vivo pharmacological studies indicate that solifenacin is a competitive inhibitor of the muscarinic M3 subtype receptor.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G04BD08 Solifenacin G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BD Urinary antispasmodics
Discover more medicines within G04BD08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VESICARE Oral suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 242478-37-1
DrugBank Drug: DB01591
KEGG Drug: D08522
PubChem Compound: 154059
RxNorm Ingredient: 322167
SNOMED-CT Concept: 407030007
Solifenacin (substance)
UNII Identifier: A8910SQJ1U
SOLIFENACIN
UNII Identifier: KKA5DLD701
SOLIFENACIN SUCCINATE

Medicines

Solifenacin is an active ingredient of these brands:

United States (US)

Albania (AL)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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