Sulbactam and Durlobactam

Therapeutic indications

Sulbactam and Durlobactam is indicated for:

Hospital-acquired pneumonia caused by susceptible isolates of Acinetobacter baumannii-calcoaceticus complex

Population group: only adults (18 years old or older)

Sulbactam/durlobactam combination is indicated in patients 18 years of age and older for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by susceptible isolates of Acinetobacter baumannii-calcoaceticus complex.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulbactam/durlobactam and other antibacterial drugs, sulbactam/durlobactam should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Sulbactam and Durlobactam is contraindicated in the following cases:

Allergy to beta-lactams

at least one of
Allergy to penicillin
Cephalosporin allergy
Cephamycin allergy
Monobactam allergy
Carbapenem allergy

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