Chemical formula: C₁₆H₂₀N₆O Molecular mass: 312.37 g/mol PubChem compound: 9926791
Tofacitinib is indicated for:
Population group: only adults (18 years old or older)
Tofacitinib in combination with methotrexate (MTX) is indicated for the treatment of moderate to severe active rheumatoid arthritis (RA) in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying antirheumatic drugs. Tofacitinib can be given as monotherapy in case of intolerance to MTX or when treatment with MTX is inappropriate.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Tofacitinib in combination with MTX is indicated for the treatment of active psoriatic arthritis (PsA) in adult patients who have had an inadequate response or who have been intolerant to a prior disease-modifying antirheumatic drug (DMARD) therapy.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Tofacitinib is indicated for the treatment of adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a biologic agent.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Tofacitinib is contraindicated in the following cases:
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