Tolbutamide

Chemical formula: C₁₂H₁₈N₂O₃S  Molecular mass: 270.348 g/mol  PubChem compound: 5505

Active ingredient description

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A10BB03 Tolbutamide A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BB Sulfonamides, urea derivatives
Discover more medicines within A10BB03
V04CA01 Tolbutamide V Various → V04 Diagnostic agents → V04C Other diagnostic agents → V04CA Tests for diabetes
Discover more medicines within V04CA01

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 64-77-7
DrugBank Drug: DB01124
KEGG Drug: D00380
PubChem Compound: 5505
RxNorm Ingredient: 10635
SNOMED-CT Concept: 373481003
Tolbutamide (substance)
UNII Identifier: 982XCM1FOI
TOLBUTAMIDE

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