Chemical formula: C₄H₁₁NO₃ Molecular mass: 121.135 g/mol PubChem compound: 6503
Trometamol acts as a proton acceptor and prevents or corrects acidosis by actively binding hydrogen ions (H+). Tromethamine also acts as an osmotic diuretic, increasing urine flow, urinary pH, and excretion of fixed acids, carbon dioxide and electrolytes. It is used for the prevention and correction of metabolic acidosis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B05BB03 | Trometamol | B Blood and blood forming organs → B05 Blood substitutes and perfusion solutions → B05B I.V. solutions → B05BB Solutions affecting the electrolyte balance |
| B05XX02 | Trometamol | B Blood and blood forming organs → B05 Blood substitutes and perfusion solutions → B05X I.V. solution additives → B05XX Other i.v. solution additives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| THAM Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Trometamol is an active ingredient of these brands:
United States (US)Brazil (BR)
France (FR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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