Varicella, live attenuated

Active ingredient description

Natural infection induces a cellular and humoral immune response to the varicella-zoster virus, which can be rapidly detected following infection. IgG, IgM and IgA directed against viral proteins usually appear at the same time that a cellular immune response can be demonstrated, making the relative contribution of humoral and cellular immunity to disease progression difficult to ascertain. Vaccination has been shown to induce both humoral and cell-mediated types of immunity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J07BK01 Varicella, live attenuated J Antiinfectives for systemic use → J07 Vaccines → J07B Viral vaccines → J07BK Varicella zoster vaccines
Discover more medicines within J07BK01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VARILRIX Powder and solvent for solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

External identifiers

DrugBank Drug: DB10318
RxNorm Ingredient: 1292422
UNII Identifier: GPV39ZGD8C
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN

Medicines

Varicella, live attenuated is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

  • VARILRIX as Varicella virus live attenuated OKA strain

  • (combination) PRIORIX TETRA as Varicella virus live attenuated OKA
  • (combination) PROQUAD

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • VARILRIX as Varicella virus live attenuated OKA strain

  • (combination) PROQUAD

Italy (IT)

Lithuania (LT)

Malta (MT)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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