Varicella, live attenuated

Pharmacodynamic properties

Varicella vaccine produces an attenuated clinically inapparent varicella infection in susceptible subjects.

The presence of antibodies is accepted as evidence of protection, however, there is no established limit of protection for varicella disease.

Pharmacokinetic properties

Evaluation of pharmacokinetic properties is not required for vaccines.

Preclinical safety data

Non-clinical data reveal no special hazard for humans based on general safety tests performed in animals.

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