Vitamin B1 Other names: Thiamine

Chemical formula: C₁₂H₁₇N₄OS+  Molecular mass: 265.355 g/mol  PubChem compound: 1130

Interactions

Vitamin B1 interacts in the following cases:

Theophylline concentration

High doses of thiamine may interfere with spectrophotometric assays of theophylline plasma concentration.

Urobilinogen determination

Thiamine could give false positive results for urobilinogen determination by the Ehrlich’s reaction.

Thiosemicarbazone, 5-fluorouracil

The thiamine antagonists thiosemicarbazone and 5-fluorouracil can neutralise the effect of thiamine. Patients using any of these treatments may need their thiamine dose adjusted.

Pregnancy

This product is not intended for use in pregnant women.

Nursing mothers

This product is not intended for use in lactating women.

Effects on ability to drive and use machines

No studies on the effect on the ability to drive and use machines have been performed.

However, patients should be cautioned to see how they react before driving or operating machinery.

Adverse reactions


Gastrointestinal disorders

Frequency not known (cannot be estimated from data): Mild gastrointestinal events such as nausea, vomiting, diarrhoea, and abdominal pain have been reported.

Immune system disorders

Frequency not known (cannot be estimated from data): Allergic and anaphylactic reactions, with symptoms of pruritus, urticaria, itching, hives, angioedema, abdominal pain, respiratory distress, tachycardia, palpitations, and shock have been reported in single cases.

Cross-check medications

Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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