Chemical formula: C₆₃H₉₁CoN₁₃O₁₄P Molecular mass: 1,344.382 g/mol PubChem compound: 71306319
Methylcobalamin is a cobalamin, a form of vitamin B12. Mecobalamin is a kind of endogenous coenzyme B12. Mecobalamin plays an important role in transmethylation as a coenzyme of methionine synthetase in the synthesis of methionine from homocysteine. Mecobalamin promotes axonal transport and axonal regeneration. Mecobalamin promotes myelination (phospholipid synthesis). Methylcobalamin is used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B03BA05 | Mecobalamin | B Blood and blood forming organs → B03 Antianemic preparations → B03B Vitamin B12 and folic acid → B03BA Vitamin B12 (cyanocobalamin and analogues) |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| METHYCOBAL Solution for injection | Υπουργείο Υγείας (CY) | MPI, EU: SmPC | |
| METHYCOBAL Tablet | Υπουργείο Υγείας (CY) | MPI, EU: SmPC |
Mecobalamin is an active ingredient of these brands:
Brazil (BR)Cyprus (CY)Hong Kong (HK)Japan (JP)Nigeria (NG)
Singapore (SG)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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