Vorasidenib

Chemical formula: C₁₄H₁₃ClF₆N₆  Molecular mass: 414.079 g/mol  PubChem compound: 117817422

Therapeutic indications

Vorasidenib is indicated for:

Non-enhancing Grade 2 astrocytoma or oligodendroglioma with an IDH1 R132 or IDH2 R172 mutation

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Voranigo as monotherapy is indicated for the treatment of predominantly non-enhancing Grade 2 astrocytoma or oligodendroglioma with an IDH1 R132 or IDH2 R172 mutation in adult and adolescent patients aged 12 years and older and weighing at least 40 kg who only had surgical intervention and are not in immediate need of radiotherapy or chemotherapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Vorasidenib is contraindicated in the following cases:

Lactation

Lactation

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