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ATC Group: A10BA Biguanides

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A10
Drugs used in diabetes
3
A10B
Blood glucose lowering drugs, excl. insulins
4
A10BA
Biguanides

Contents

Code
Title
A10BA01
Phenformin
A10BA02
Metformin
A10BA03
Buformin

Active Ingredients

Chemical substance
Description
Metformin

Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia.

Phenformin

Phenformin is a biguanide hypoglycemic agent with actions and uses similar to those of metformin. It activates AMP-activated protein kinase (AMPK) and inhibits mTORC1 signaling. Phenformin used for the treatment of diabetes. Phenformin exerts potential anti-neoplastic action.

Monographs

Monograph
Type
Country
GLUCOPHAGE / GLUCOPHAGE XR Tablet / Extended-release tablet
MPI, US: SPL/PLR
US
GLUMETZA Film coated tablet, extended release
MPI, US: SPL/PLR
US
METFORMIN Oral Solution
MPI, EU: SmPC
UK