The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
A | Alimentary tract and metabolism | |
2
|
A10 | Drugs used in diabetes | |
3
|
A10B | Blood glucose lowering drugs, excl. insulins | |
4
|
A10BA | Biguanides |
| Code | Title | |
|---|---|---|
| A10BA01 | Phenformin | |
| A10BA02 | Metformin | |
| A10BA03 | Buformin |
| Active Ingredient |
|---|
|
|
|
Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia. |
|
Phenformin is a biguanide hypoglycemic agent with actions and uses similar to those of metformin. It activates AMP-activated protein kinase (AMPK) and inhibits mTORC1 signaling. Phenformin used for the treatment of diabetes. Phenformin exerts potential anti-neoplastic action. |
| Document | Type | Information Source | |
|---|---|---|---|
| BROT Film-coated tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) | |
| DIABETMIN Prolonged release tablet | MPI, EU: SmPC | Marketing Authorisation Holder | |
| DIAFORMIN Film-coated tablet | MPI, EU: SmPC | Pharmaceutical Benefits Scheme (AU) | |
| GLUCOPHAGE Film-coated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| GLUCOPHAGE Tablet / Extended-release tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| GLUMETZA Film coated tablet, extended release | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| GLYFORMIN Film-coated tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) | |
| METFORAL Film-coated tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) | |
| ROMIDAB Film-coated tablet | MPI, Generic | Health Products Regulatory Authority (ZA) | |
| SIOFOR Prolonged-release tablet | MPI, EU: SmPC | Health Products Regulatory Authority (IE) |