ATC Group: N05BA Benzodiazepine derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N05BA in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N05 Psycholeptics
3 N05B Anxiolytics
4 N05BA Benzodiazepine derivatives

Group N05BA contents

Code Title
N05BA01 Diazepam
N05BA02 Chlordiazepoxide
N05BA03 Medazepam
N05BA04 Oxazepam
N05BA05 Potassium clorazepate
N05BA06 Lorazepam
N05BA07 Adinazolam
N05BA08 Bromazepam
N05BA09 Clobazam
N05BA10 Ketazolam
N05BA11 Prazepam
N05BA12 Alprazolam
N05BA13 Halazepam
N05BA14 Pinazepam
N05BA15 Camazepam
N05BA16 Nordazepam
N05BA17 Fludiazepam
N05BA18 Ethyl loflazepate
N05BA19 Etizolam
N05BA21 Clotiazepam
N05BA22 Cloxazolam
N05BA23 Tofisopam
N05BA24
N05BA25
N05BA56 Lorazepam, combinations

Active ingredients in N05BA

Active Ingredient Description
Alprazolam

Alprazolam, like other benzodiazepines, has a high affinity for the benzodiazepine binding site in the brain. It facilitates the inhibitory neurotransmitter action of gamma-aminobutyric acid, which mediates both pre- and post synaptic inhibition in the central nervous system (CNS).

Bentazepam
Bromazepam

Bromazepam is a pyridylbenzodiazepine compound with anxiolytic properties.

Chlordiazepoxide

Chlordiazepoxide has anxiolytic and central muscle relaxant properties. It has little autonomic activity. Chlordiazepoxide acts as depressant of the central nervous system producing all levels of CNS depression, from mild sedation to hypnosis, to coma depending on the dose.

Clobazam

Clobazam is a 1,5-benzodiazepine and the pharmacodynamic activity is qualitatively similar to that of other compounds of the class of Muscle relaxant, Anxiolytic, Sedative, Hypnotic, Anticonvulsant, Amnesic.

Clorazepate

Clorazepate is a benzodiazepine with anxiolytic, sedative, hypnotic, and anticonvulsant properties. Clorazepate exerts its effect by de-activating the nervous system through potentiation of the inhibitory effect of gamma-aminobutyric acid (GABA) on the GABA-A receptors by binding to a site that is distinct from the GABA binding site.

Clotiazepam
Cloxazolam
Diazepam

Diazepam is a psychotropic substance from the class of 1,4-benzodiazepines with marked properties of suppression of tension, agitation and anxiety as well as sedative and hypnotic effects. In addition, diazepam demonstrates muscle relaxant and anticonvulsive properties. It is used in the short-term treatment of anxiety and tension states, as a sedative and premedicant, in the control of muscle spasm and in the management of alcohol withdrawal symptoms.

Ethyl loflazepate
Etizolam
Fludiazepam
Flutazolam
Halazepam
Ketazolam
Lorazepam

Lorazepam is a benzodiazepine with anxiolytic, sedative and hypnotic properties.

Medazepam
Mexazolam

Mexazolam is a benzodiazepine indicated for the management of anxiety disorder associated or not to psychoneurotic conditions. The exact sites and mode of action have not been fully elucidated, but it appears to be mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), by the stimulation of specific receptors. Both GABA and chloride may enhance the binding to those receptors.

Desmethyldiazepam

Nordazepam is a 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively. Nordazepam has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety.

Oxazepam

Oxazepam is a synthetic benzodiazepine derivative with anxiolytic and sedative hypnotic properties. Although the mechanism of action has not been fully elucidated, oxazepam appears to enhance gamma-aminobutyric acid (GABA) receptor affinity for GABA, thereby prolonging synaptic actions of GABA.

Oxazolam
Pinazepam
Prazepam

Prazepam is a benzodiazepine derivative and has depressant effects on the central nervous system. Benzodiazepines act at the level of the limbic, thalamic, and hypothalamic regions of the CNS and can produce any level of CNS depression required including sedation, hypnosis, skeletal muscle relaxation, and anticonvulsant activity.

Tofisopam

Tofisopam is an atypical benzodiazepine derivative. It has an anxiolytic effect, almost not-accompanied by a sedative, muscle relaxant, anticonvulsant action. Tofisopam is a psychovegetative regulator, it eliminates various forms of autonomic disorders. It has a mild stimulating activity. Due to the lack miorelaxant effect tofisopam can also be used in patients with myopathy and myasthenia.

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