ATC Group: P01BE Artemisinin and derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of P01BE in the ATC hierarchy

Level Code Title
1 P Antiparasitic products, insecticides and repellents
2 P01 Antiprotozoals
3 P01B Antimalarials
4 P01BE Artemisinin and derivatives

Group P01BE contents

Code Title
P01BE01 Artemisinin
P01BE02 Artemether
P01BE03 Artesunate
P01BE04 Artemotil
P01BE05 Artenimol

Active ingredients in P01BE

Active Ingredient Description
Artemether

Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including infections acquired in chloroquine-resistant areas.

Artemisinin

Artemisinin is used in the treatment of malaria due to species Plasmodium.

Artemotil

Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.

Artenimol

Artenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated Plasmodium falciparum infections. Artemisinin combination therapy is highly effective against malaria.

Artesunate

Artesunate is a semi-synthetic artemisinin derivative, indicated for the initial treatment of severe malaria in adults and children. The antimalarial mechanism of action of artesunate is generally thought to depend upon activation involving iron-mediated cleavage of the endoperoxide bridge of DHA to generate an unstable organic free radical followed by alkylation, where the free radical binds to malarial proteins leading to destruction of parasite membranes.