HISTALIX D.M.

This brand name is authorized in South Africa

Active ingredients

The drug HISTALIX D.M. contains a combination of these active pharmaceutical ingredients (APIs):

1 Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE

Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors.

Read about Demorphan
2 Diphenhydramine
UNII TC2D6JAD40 - DIPHENHYDRAMINE HYDROCHLORIDE

Diphenhydramine is an ethanolamine-derivative antihistamine. It is an antihistamine with anticholinergic and marked sedative effects. It acts by inhibiting the effects on H1-receptors. Diphenhydramine is effective in reducing sleep onset (i.e., time to fall asleep) and increasing the depth and quality of sleep.

Read about Diphenhydramine
3 Ammonium chloride
UNII 01Q9PC255D - AMMONIUM CHLORIDE
Read about Ammonium chloride

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: ZA Health Products Regulatory Authority Identifier(s): X/10.1/400

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