Active Ingredient: Aminolevulinic acid
5-aminolevulinic acid is indicated in adult for visualisation of malignant tissue during surgery for malignant glioma (WHO grade III and IV).
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 20 milligrams aminolevulinic acid per kilogram of body weight, one dose.
The recommended dose is 20 mg 5-aminolevulinic acid hydrochloride (5-ALA HCl) per kilogram body weight.
The 5-ALA solution should be administered orally three hours (range 2-4 hours) before anaesthesia. Use of 5-ALA under conditions other than the ones used in the clinical trials entail an undetermined risk.
If the surgery is postponed by more than 12 hours, surgery should be re-scheduled for the next day or later. Another dose of this medicine can be taken 2–4 hours before anaesthesia.
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