LOMOTIL Tablet Ref.[50639] Active ingredients: Atropine Diphenoxylate

Source: Health Products and Food Branch (CA)  Revision Year: 2019 

Detailed pharmacology

The mode of action of diphenoxylate in the bowel is similar to that of morphine and related drugs. Gastrointestinal propulsion is inhibited through a direct action on the smooth muscle, resulting in a decrease in peristaltic action and a consequent increase in transit time.

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