Atropine

Chemical formula: C₁₇H₂₃NO₃  Molecular mass: 289.369 g/mol  PubChem compound: 174174

Active ingredient description

Atropine is an antimuscarinic agent which competitively antagonises acetylcholine at postganglionic nerve endings, thus affecting receptors if the exocrine glands, smooth muscle, cardiac muscle and the central nervous system.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A03BA01 Atropine A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03B BELLADONNA AND DERIVATIVES, PLAIN → A03BA Belladonna alkaloids, tertiary amines
Discover more medicines within A03BA01
S01FA01 Atropine S Sensory organs → S01 Ophthalmologicals → S01F Mydriatics and cycloplegics → S01FA Anticholinergics
Discover more medicines within S01FA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ATROPINE Eye drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ISOPTO ATROPINE Ophthalmic solution FDA, National Drug Code (US) MPI, US: SPL/PLR
ATROPINE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ATROPINE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 55-48-1
DrugBank Drug: DB00572
KEGG Drug: D00113
PubChem Compound: 174174
RxNorm Ingredient: 1223
SNOMED-CT Concept: 372832002
Atropine (substance)
UNII Identifier: 7C0697DR9I
ATROPINE

Medicines

Atropine is an active ingredient of these brands:

United States (US)

Australia (AU)

  • ATROPT as ATROPINE SULFATE

  • (combination) LOFENOXAL as ATROPINE SULFATE
  • (combination) LOMOTIL as ATROPINE SULFATE

Brazil (BR)

Canada (CA)

Ecuador (EC)

  • (combination) LOMOTIL as ATROPINE SULFATE

Estonia (EE)

France (FR)

  • (combination) INEUROPE as ATROPINE SULFATE

Hong Kong (HK)

  • ATROSOL as ATROPINE SULFATE

  • (combination) CELIDIN as ATROPINE SULFATE
  • (combination) DHAMOTIL as ATROPINE SULFATE
  • (combination) DIAMOTIL as ATROPINE SULFATE
  • (combination) SYNCOMIL as ATROPINE SULFATE

Israel (IL)

Japan (JP)

Malta (MT)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

  • ATROSOL as ATROPINE SULFATE

  • (combination) BEAMOTIL as ATROPINE SULFATE
  • (combination) DHAMOTIL as ATROPINE SULFATE
  • (combination) LOMOTIL as ATROPINE SULFATE
  • (combination) SUN-DIANOX as ATROPINE SULFATE

South Africa (ZA)

  • (combination) LOMOTIL as ATROPINE SULFATE

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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