Atropine
Therapeutic Indications
Atropine is indicated for:
Refraction
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old)
Atropine sulfate is an antimuscarinic agent used as a cycloplegic and mydriatic.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Ophthalmic - 1 drop once
Iritis, uveitis
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old)
The eye drops are used in the treatment of iritis and uveitis to immobilise the iris and ciliary muscle and to prevent or break down adhesions.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Ophthalmic - 1-3 drops in 1-3 divided doses
Irritable bowel syndrome
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Oral - 0.6-1.2 mg once
Non ulcer dyspepsia
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Oral - 0.6-1.2 mg once
Diverticular disease
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Oral - 0.6-1.2 mg once
Prophylaxis of vagal autonomic bradycardia during anaesthesia, salivary and bronchial secretions reduction
Irrespective of gender only Adults (18 years old or older)
Atropine is used in anaesthesia, to reduce the risk of vagal inhibition of the heart and to reduce salivary and bronchial secretions.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intramuscular - 0.3-0.6 mg once
Treatment 2: Intravenous - 0.3-0.6 mg once
Treatment 3: Subcutaneous - 0.3-0.6 mg once
Reversal of neuromuscular blockade
Irrespective of gender only Adults (18 years old or older)
Atropine is used in conjunction with neostigmine which is used to reverse the effects of non-depolarising muscle relaxants.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intramuscular - 0.6-1.2 mg once
Refraction
Irrespective of gender only Adults (18 years old or older)
Atropine sulfate is an antimuscarinic agent used as a cycloplegic and mydriatic.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Ophthalmic - 1-2 drop once
Iritis, uveitis
Irrespective of gender only Adults (18 years old or older)
The eye drops are used in the treatment of iritis and uveitis to immobilise the iris and ciliary muscle and to prevent or break down adhesions.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Ophthalmic - 2-8 drops in 1-4 divided doses
Poisoning by organo-phosphorous compounds
Irrespective of gender only Adults (18 years old or older)
Atropine is used in the treatment of poisoning by certain cholinesterase inhibitors e.g. organo-phosphorous compounds.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 1.2-2 mg once
Treatment 2: Intramuscular - 1.2-2 mg once
Cholinergic crisis
Irrespective of gender only Adults (18 years old or older)
Treatment of cholinergic crisis of myasthenia gravis.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 0.4-2 mg once
Cardiopulmonary resuscitation
Irrespective of gender only Adults (18 years old or older)
During cardiopulmonary resuscitation to counteract excessive vagal tone on the heart.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 0.2-0.5 mg once
Prophylaxis of vagal autonomic bradycardia during anaesthesia, salivary and bronchial secretions reduction
Irrespective of gender only Minors (0 - 18 years old)
Atropine is used in anaesthesia, to reduce the risk of vagal inhibition of the heart and to reduce salivary and bronchial secretions.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intramuscular - 10-20 ug/kg once
Treatment 2: Intravenous - 10-20 ug/kg once
Treatment 3: Subcutaneous - 10-20 ug/kg once
Poisoning by organo-phosphorous compounds
Irrespective of gender only Minors (0 - 18 years old)
Atropine is used in the treatment of poisoning by certain cholinesterase inhibitors e.g. organo-phosphorous compounds.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 50 ug/kg once
Treatment 2: Intramuscular - 50 ug/kg once
Contraindications
Active ingredient Atropine is contraindicated in the following cases:
Prostatic hypertrophy
No gender/age discrimination
Narrow-angle glaucoma
No gender/age discrimination
Paralytic ileus, pyloric stenosis, toxic megacolon, severe ulcerative colitis, reflux oesophagitis
No gender/age discrimination
Thyrotoxicosis
No gender/age discrimination
Myasthenia gravis
No gender/age discrimination
Myasthenia gravis (except when given with an anticholinesterase). No absolute contraindication to atropine in Advanced Cardiovascular Life Support (ACLS) or severe bradycardia.