Diphenoxylate

Chemical formula: C₃₀H₃₂N₂O₂  Molecular mass: 452.587 g/mol  PubChem compound: 13505

Active ingredient description

Diphenoxylate is a synthetic opioid derivative with selective effects on gastrointestinal smooth muscle. It is essentially devoid of “morphine type subjective effects” at therapeutic doses.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A07DA01 Diphenoxylate A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07D Antipropulsives → A07DA Antipropulsives
Discover more medicines within A07DA01

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 915-30-0
DrugBank Drug: DB01081
KEGG Drug: D00301
PubChem Compound: 13505
RxNorm Ingredient: 3500
SNOMED-CT Concept: 15052009
Diphenoxylate (substance)
SNOMED-CT Concept: 317360000
Diphenoxylate (substance)
UNII Identifier: 73312P173G
DIPHENOXYLATE

Medicines

Diphenoxylate is an active ingredient of these brands:

United States (US)

  • (combination) LOMOTIL as DIPHENOXYLATE HYDROCHLORIDE

Australia (AU)

Canada (CA)

  • (combination) LOMOTIL as DIPHENOXYLATE HYDROCHLORIDE

Ecuador (EC)

  • (combination) LOMOTIL as DIPHENOXYLATE HYDROCHLORIDE

Hong Kong (HK)

  • (combination) CELIDIN as DIPHENOXYLATE HYDROCHLORIDE
  • (combination) DHAMOTIL as DIPHENOXYLATE HYDROCHLORIDE
  • (combination) DIAMOTIL as DIPHENOXYLATE HYDROCHLORIDE
  • (combination) SYNCOMIL as DIPHENOXYLATE HYDROCHLORIDE

Poland (PL)

  • (combination) REASEC as DIPHENOXYLATE HYDROCHLORIDE

Singapore (SG)

  • (combination) BEAMOTIL as DIPHENOXYLATE HYDROCHLORIDE
  • (combination) DHAMOTIL as DIPHENOXYLATE HYDROCHLORIDE
  • (combination) LOMOTIL as DIPHENOXYLATE HYDROCHLORIDE
  • (combination) SUN-DIANOX as DIPHENOXYLATE HYDROCHLORIDE

South Africa (ZA)

  • (combination) LOMOTIL as DIPHENOXYLATE HYDROCHLORIDE

Turkey (TR)

  • (combination) LOMOTIL as DIPHENOXYLATE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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