Source: Registered Drug Product Database (NG) Revision Year: 2025 Publisher: SAM PHARMACEUTICALS LIMITED., 2, WESTERN RESERVOIR ROAD, ILORIN, KWARA STATE, NIGERIA, 08057075266, sampharmaceuticalltd@gmail.com
Prednisolone is used in physiological doses for replacement therapy in adrenal insufficiency and in pharmacological doses for their anti-inflammatory and immunosuppressant glucocorticoid properties.
The lowest effective dose should be used for the minimum period in order to minimise side effects.
The initial dosage may vary from 5 mg to 60 mg daily in divided doses, as a single dose in the morning after breakfast, or as a double dose on alternate days. Dosage depends on the disorder being treated. The dose can often be reduced within a few days but may need to be continued for several weeks or months. 2.5 to 15 mg daily, but higher doses may be needed. Cushingoid side-effects are more likely above 7.5 mg daily.
Treatment of elderly patients, particularly if long-term, should be planned bearing in mind the more serious consequences of the common side-effects of corticosteroids in old age.
Although appropriate fractions of the actual dose may be used, dosage will usually be determined by clinical response as in adults. Prednisolone should be used only when specifically indicated, in a minimal dosage and for the shortest possible time.
The tablet is an oral administration and should be taken with or after food.
Reports of acute toxicity and/or death following overdosage of glucocorticoids are rare. No specific antidote is available; treatment is supportive and symptomatic.
24 months.
Protect from light and store in a cool dry place below 30°C.
Blister with Transparent PVC/Aluminium foil. Packs of 10 × 10 tablets in a carton.
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