Abacavir

Active ingredient description

Abacavir is a potent selective inhibitor of HIV-1 and HIV-2. The mechanism of action as to HIV, is the inhibition of the enzyme reverse transcriptase of HIV, an event that causes chain termination and stopping the replication cycle of the virus.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
J05AF06
Abacavir
J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
Discover more medicines within J05AF06

Medicines

$substanceName is the active ingredient of these drugs:

Drug
Countries
ABAMAT

South Africa

ABAMUNE

South Africa

ABAVAID

South Africa

ACAVIROX

Ecuador

BACAMUNE

South Africa

BAVIR

South Africa

HETACAV

South Africa

INVERTRON

South Africa

KAVIMUN PAED

South Africa

ZIAGEN

Australia Austria Canada Cyprus Estonia

ZIAGENAVIR

Brazil

$substanceName is also found within below combination drugs:

ABAVILAM , AZADAR , BACATAC , COABLAM , DUMIVA , EPZICOM , HETERUAM , KIVALA , KIVEXA , MYLAMBA , PROFELVIR , QUADRIMUNE , QULAM-CO , RETRIKIL , TERZALA , TRELAVUE , TRIUMEQ , TRIZIVAR , TRIZIVIR , VIROXIAL , VIRULATE , VUBIR , VUDIMAX

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
ZIAGEN Film-coated tablet
Summary of Product Characteristics (SPC)
ZIAGEN Oral solution
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Molecular mass: 286.332 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 136470-78-5
DrugBank Drug: DB01048
KEGG Drug: D07057
RxNorm Ingredient: 190521
SNOMED-CT Concept: 387005008
Abacavir (substance)
UNII Identifier: WR2TIP26VS
ABACAVIR
 
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