Chemical formula: C₁₄H₁₈N₆O  Molecular mass: 286.332 g/mol  PubChem compound: 441300

Therapeutic indications

Abacavir is indicated for:

Human immunodeficiency virus infection

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Abacavir is indicated in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection in adults, adolescents and children.

The demonstration of the benefit of abacavir is mainly based on results of studies performed with a twice daily regimen, in treatment-naïve adult patients on combination therapy.

Before initiating treatment with abacavir, screening for carriage of the HLA-B*5701 allele should be performed in any HIV-infected patient, irrespective of racial origin. Abacavir should not be used in patients known to carry the HLA-B*5701 allele.

For this indication, competent medicine agencies globally authorize below treatments (click for details):


Abacavir is contraindicated in the following cases:

Positive HLA-B*5701 status

HLA-B*57:01 positive

End-stage renal disease

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)



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