Aliskiren

Therapeutic indications

Aliskiren is indicated for:

Essential hypertension

Population group: both men and women, only adults (18 years old or older)

Aliskiren is indicated for the treatment of essential hypertension in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

150-300 mg once daily

Contraindications

Aliskiren is contraindicated in the following cases:

Hereditary or idiopathic angioedema

at least one of
Idiopathic angio-oedema

Hereditary angioneurotic edema

Pregnancy

Pregnancy

Breast-feeding

Lactation

P-gp inhibitors

P-glycoprotein inhibitors

ACEI, ARB in patients with diabetes mellitus or renal impairment

at least one of
ACE inhibitors, plain

Angiotensin II antagonists, plain
and additionally at least one of
Diabetes mellitus




Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)