Aliskiren

Chemical formula: C₃₀H₅₃N₃O₆  Molecular mass: 551.758 g/mol  PubChem compound: 5493444

Therapeutic indications

Aliskiren is indicated for:

Essential hypertension

Population group: only adults (18 years old or older)

Aliskiren is indicated for the treatment of essential hypertension in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Aliskiren is contraindicated in the following cases:

Hereditary or idiopathic angioedema

at least one of
Idiopathic angio-oedema
Hereditary angioneurotic edema

Pregnancy

Pregnancy

Breast-feeding

Lactation

P-gp inhibitors

P-glycoprotein inhibitors

ACEI, ARB in patients with diabetes mellitus or renal impairment

at least one of
ACE inhibitors, plain
Angiotensin II antagonists, plain and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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